Ali Deniz Dalgıç

BIOE 334 Biyomalzemeler

BIOE 221 Endüstriyel Mikrobiyoloji

BIOE 323 Genetik Mühendisliği I

BIOE 323 Genetik Mühendisliği II

Projeler

1) ODTÜ, Mühendislik Bilimleri Bölümü, BAP-08-11-2012-016, Baş.Tarihi: 01.01.2012 Bitiş Tarihi: 31.12.2013 “Antikanser İlaç İçeren ve CD20 Karşıtı Antikor ile Hedefli Yeni Lipozomal Sistemin Lösemi ve Lenfoma Hastalıkları Tedavisinde In vitro Etkinliğinin Araştırılması”, Araştırmacı

2) ODTÜ, Mühendislik Bilimleri Bölümü, BAP-07-02-2014-007-610, Baş.Tarihi: 01.01.2014 Bitiş Tarihi: 31.12.2016, Fen bilimleri enstitüsü /lisansüstü tez projesi. Araştırmacı

3) TÜBİTAK 1001, proje no: 215M893, Baş.Tarihi: 01.05.2016 Bitiş Tarihi: 13.02.2019 “Diatom Silika İskeletleri ile Güçlendirilmiş Polihidroksibutirat-kohidroksivalerat/Pullulan Üç Boyutlu Doku İskelelerinin Kemik Doku Mühendisliğinde Kullanılabilirliğinin Araştırılması” Bursiyer

4) ODTÜ, Mühendislik Bilimleri Bölümü, GAP-310-2022-10875, Baş.Tarihi: 17.01.2022 Bitiş Tarihi: 17.01.2023, “Menadione (Vitamin K3) and Doxorubicin dual loaded liposomes for enhanced anticancer effect.” Araştırmacı

5) İstanbul Bilgi Üniversitesi, Genetik ve Biyomühendislik Bölümü BAP proje no: 2021.02.005, Baş.Tarihi: 01.04.2022 Bitiş Tarihi: 01.07.2024. "Meme Kanseri Tümör Alımı Operasyonu Sonrası Tedaviye Yönelik Lokal Talidomid Salımı İçin Hücre Taşıyıcı/Lipozom Sisteminin Geliştirilmesi (Proje No: 2021.02.005)" Yürütücü

6) TÜBİTAK 3501, Istanbul Bilgi University, Dept. of Genetics and Bioengineering, 01.09.2023-Continues. "Characterization of hybrid epithelial-mesenchymal transition states in cancer cells and identification of drug candidate molecules targeting hybrid states.” (Project No: 121Z680)" Araştırmacı

7) HORIZON 2020, PRIMA S2 Call multi-topics 2023 STEP 2, 01.06.2024-Devam etmekte, “Nano-Enabled Antimicrobial Food Packaging Incorporating Natural Bioactives from Mediterranean Agri-Wastes” Araştırmacı

8) TÜBİTAK 1001, Istanbul Bilgi University, Dept. of Genetics and Bioengineering, 14.07.2024-Devam ediyor. "Alizarin Taşıyan Yerli Diatom Biyosilika Ile Enfeksiyon Tayini Yapabilen Akıllı Ve Aktif Yara Örtüsü Üretimi” (Project No: 124M489)" Yürütücü

Yayınlar

1. Dalgic, A. D., Tezcaner, A., Elci, P., Sarper, M., Arpaci, F., Avcu, F., & Keskin, D. (2016). Improvement of a liposomal formulation with a native molecule: calcitriol. RSC Advances, 6(83), 80158-80167.

2. Gurturk, Z., Tezcaner, A., Dalgic, A. D., Korkmaz, S., & Keskin, D. (2017). Maltodextrin modified liposomes for drug delivery through the blood–brain barrier. MedChemComm, 8(6), 1337-1345.

3. Dalgic, A. D., Alshemary, A. Z., Tezcaner, A., Keskin, D., & Evis, Z. (2018). Silicate-doped nano-hydroxyapatite/graphene oxide composite reinforced fibrous scaffolds for bone tissue engineering. Journal of Biomaterials Applications, 32(10), 1392-1405.

4. Caliskan, Y., Dalgic, A. D., Gerekci, S., Gulec, E. A., Tezcaner, A., Can, O. & Keskin, D. (2019). A new therapeutic combination for osteosarcoma: Gemcitabine and Clofazimine co-loaded liposomal formulation. International Journal of Pharmaceutics, 557, 97–104.

5. Alshemary, A. Z., Pazarçeviren, E. A., Dalgic, A. D., Tezcaner, A., Keskin, D., & Evis, Z. (2019). Nanocrystalline Zn2+ and SO42− binary doped fluorohydroxyapatite: A novel biomaterial with enhanced osteoconductive and osteoinconductive properties. Materials Science and Engineering: C, 104, 109884.

6. Dalgic, A. D., Atila, D., Karatas, A., Tezcaner, A., & Keskin, D. (2019). Diatom shell incorporated PHBV/PCL-pullulan co-electrospun scaffolds for bone tissue engineering. Materials Science and Engineering: C, 100, 735-746.

7. Alissa Alam, H., Dalgic, A. D., Tezcaner, A., Ozen, C., & Keskin, D. (2020). A comparative study of monoaxial and coaxial PCL/gelatin/Poloxamer 188 scaffolds for bone tissue engineering. International Journal of Polymeric Materials and Polymeric Biomaterials, 69(6), 339-350.

8. Motemeni, A., Dalgic, A. D., Alshemary, A. Z., Keskin, D., & Evis, Z. (2020). Structural and Biological Analysis of Mesoporous Lanthanum Doped βTCP For Potential Use as Bone Graft Material. Materials Today Communications, 23, 101151.

9. Guner, M. B., Dalgic, A. D., Tezcaner, A., Yilanci, S., & Keskin, D. (2020). Dual phase scaffold produced by rotary jet spinning and electrospinning for tendon tissue engineering. Biomedical Materials, 15(6), 065014.

10. Motemeni, A., Alshemary, A. Z., Dalgic, A. D., Keskin, D., & Evis, Z. (2021). Lanthanum doped dicalcium phosphate bone cements for potential use as filler for bone defects. Materials Today Communications, 26, 101774.

11. Erener, T., Ceritoğlu, K. U., Aktekin, C. N., Dalgic, A. D., Keskin, D., Geneci, F., Ocak, M., Bilecenoğlu, B., Hücümenoğlu, S., Çaydere, M., Şeneş, M. & Sezgin, Ö. (2021). Investigation of The Effect of Ghrelin on Bone Fracture Healing in Rats. Clinical and Experimental Pharmacology and Physiology, 48 (10), 1382-1390.

12. Dalgic, A. D., Koman, E., Karatas, A., Tezcaner, A., & Keskin, D. (2021). Natural origin bilayer pullulan-PHBV scaffold for wound healing applications. Materials Science and Engineering: C, 112554.

13. Alshemary, A. Z., Hussain, R., Dalgic, A. D., & Evis, Z. (2022). Bactericidal and in vitro osteogenic activity of nano sized cobalt-doped silicate hydroxyapatite. Ceramics International, 48(19), 28231-28239.

14. Motameni, A., Alshemary, A. Z., Dalgic, A. D., Keskin, D., & Evis, Z. (2022). Graphene oxide reinforced doped dicalcium phosphate bone cements for bone tissue regenerations. Journal of the Australian Ceramic Society, 58(5), 1633-1647.

15. Dalgic, A. D., Atila, D., Tezcaner, A., Gürses, S., & Keskin, D. (2023). Diatom Silica Frustules-Doped Fibers for Controlled Release of Melatonin for Bone Regeneration. European Polymer Journal, 111858.

16. Barer, N., Tunc, B., Yilmaz, B., Ng, Y. Y., & Dalgic, A. D. (2024). Using embossing ice particulate method to prepare polyvinyl alcohol/pullulan hydrogels with surface open pores loaded with microspheres for breast cancer treatment. Journal of Drug Delivery Science and Technology, 105351.

17. Atila, D., Dalgic, A. D., Krzemińska, A., Pietrasik, J., Gendaszewska‐Darmach, E., Bociaga, D., ... & Kumaravel, V. (2024). Injectable Liposome‐Loaded Hydrogel Formulations with Controlled Release of Curcumin and α‐Tocopherol for Dental Tissue Engineering. Advanced Healthcare Materials, 2400966.