Prof.

Ster Irmak Sav

+90 212 311 5079

Dolapdere / 158

Education

  • 2014, Associate Prof., Medical Biochemistry
  • 2007, PhD., Natural Sciences, Biochemistry, Essen-Duisburg University, Germany.
  • 2001, MS., Biochemistry, Hacettepe University, Turkey.
  • 1998, BS., Chemistry , Selcuk University, Turkey.

Courses

  • NUT 103 Basic Chemistry, Fall
  • NUT 105 Human Biology, Fall
  • NUT 201 Nutritonal Biochemistry, Fall
  • HS 202 Biochemistry, Fall
  • NUT 104 Organic Chemistry, Spring
  • NUT 214 Nutrient Metabolism, Spring
  • SCI 110 Human Biology, Fall and Spring (fully online)

Areas of Interest

  • Tissue Engineering
  • Tumor Angiogenesis
  • Proteomics and Tumor Markers
  • Molecular Imaging of Tumor
  • Cell Biology
  • Protein Biochemistry
  • Biomaterials

Other Information

Academic Appointments

  • 2019-present, Professor Dr., Istanbul Bilgi University, Dept. of Nutrition and Dietetics
  • 2014-present, Associate Professor, Istanbul Bilgi University, Dept. of Nutrition and Dietetics
  • 2013-2014, Assistant Professor, Istanbul Bilgi University, Dept. of Nutrition and Dietetics
  • 2011-2013, Postdoctoral Fellow, Sabancı University, Dept. of Molecular Biology and Genetics
  • 2010-2011, Postdoctoral Fellow, High Institute of Technology İzmir, Dept. of Chemisrty
  • 2007-2010, Postdoctoral Researcher and Faculty Member, University Hospital of Duisburg-Essen, Dept. of Anatomy./ Germany
  • 2006-2007, PhD Fellow,  University Hospital of Duisburg-Essen, Dept. of Anatomy./ Germany
  • 2002-2006, PhD Fellow,  University Hospital of Hamburg-Eppendorf, Dept. of Anatomy/Urology./ Germany 


Selected Publications

  • Upcin B, Henke E, Kleefeldt F, Hoffmann H, Rosenwald A, Irmak-Sav S, Aktas HB, Rückschloß U, Ergün S. Contribution of Adventitia-Derived Stem and Progenitor Cells to New Vessel Formation in Tumors. Cells. 2021 Jul 7;10(7):1719. doi: 10.3390/cells10071719.
  • Rossow L, Veitl S, Vorlová S, Wax JK, Kuhn AE, Maltzahn V, Upcin B, Karl F, Hoffmann H, Gätzner S, Kallius M, Nandigama R, Scheld D, Irmak S, Herterich S, Zernecke A, Ergün S, Henke E. LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy. Oncogene. 2018 May 21. doi: 10.1038/s41388-018-0320-2.
  • Unal S, Ekren N, Sengil AZ, Oktar FN, Irmak S, Oral O, Sahin YM, Kilic O, Agathopoulos S, Gunduz O. Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride. J Biomed Mater Res B Appl Biomater. 2017 Nov 23. doi: 10.1002/jbm.b.34046.
  • Gokalp D, Tuzcu A, Irmak S, Bahceci M, Demirpence O., Frequency of Aspirin Resistance in Patients with Type 1 and 2 Diabetes Mellitus and its Association with Metabolic Parameters. Int. J. Of Surgery and Medicine. 2016 2(3):122-126. DOI: 10.5455
  • Kucukgul C, Ozler SB, Inci I, Karakas E, Irmak S, Gozuacik D, Taralp A, Koc B., 3D Bioprinting of Biomimetic Aortic Vascular Constructs with Self-Supporting Cells. Biotechnol Bioeng. 2014 Nov 11. doi: 10.1002/bit.25493.
  • Blois SM, Tirado-González I, Wu J, Barrientos G, Johnson B, Warren J, Freitag N, Klapp BF, Irmak S, Ergun S, Dveskler GS.,Early expression of pregnancy specific glycoprotein 22 (PSG22) by trophoblast cells modulates angiogenesis in mice, Biol Reprod. 2012 Jun 28;86(6):191. Print 2012 Jun.
  • Ha CT, Wu JA, Irmak S, Lisboa FA, Dizon AM, Warren JW, Ergun S, Dveksler GS, Human Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Has a Potential Role in Placental Vascular Morphogenesis, Biopol Reprod. 2010 March, 83, 27-35.
  • Ster Irmak, Leticia Oliveira-Ferrer, Bernhard B. Singer, Suleyman Ergun, Derya Tilki. Pro-angiogenic properties of Orosomucoid (ORM), Experimental Cell Research, 2009 Nov 1;315(18):3201-9. Epub 2009 Aug 3.
  • Tilki D, Singer BB, Shariat SF, Behrend A, Fernando M, Irmak S, Buchner A, Hooper AT, Stief SG, Reich O, Ergun S. CEACAM1: A novel urinary marker for bladder cancer detection, Eur. Urol. 2010 May, 3069, no of pages 7.          
  • Derya Tilki, Michael Seitz, Bernhard B. Singer, Ster Irmak, Oliver Reich, Christian G. Stief, Suleyman Ergun. Molecular imaging of tumor blood vessels in prostate cancer, Anticancer Res. 2009 May; 29(5):1823-9.
  • Nerbil Kilic, Leticia Oliveira-Ferrer, Samira Neshat-Vahid, Ster Irmak, Kirstin Obst- Pernberg, Jan-Henner Wurmbach, Sonja Loges, Ergin Kilic, Joachim Weil, Heidrun Lauke, Derya Tilki, Bernhard B. Singer, and Suleyman Ergun. Lymphatic reprogramming of micro vascular endothelial cells by CEA-related Cell Adhesion Molecule-1 via interaction with VEGFR-3 and Prox1.  Blood, August 30, 2007.
  • Tilki D, Irmak S, Oliveira-Ferrer L, Hauschild J, Miethe K, Atakaya H, Hammerer P, Friedrich MG, Schuch G, Galalae R, Stief CG, Kilic E, Huland H, Ergun S. CEA-related cell adhesion molecule-1 is involved in angiogenic switch in prostate cancer, Oncogene, 25(36) (2006),4965-74.
  • Ster Irmak, Derya Tilki, Jochen Heukeshoven, Leticia Oliveira-Ferrer, Martin Friedrich, Hartwig Huland, Suleyman Ergun, Stage-Dependent Increase of Orosomucoid and Zinc alpha-2 Glycoprotein in Urinary Bladder Cancer, Proteomics  5(16) (2005),4296- 304.
  • L.Oliveira-Ferrer, Derya Tilki, Gudrun Ziegeler, Jessica Hauschild, Sonja Loges, Ster Irmak, Ergin Kilic, Hartwig Huland, Martin Friedrich, Suleyman Ergun, Dual Role of CEACAM1 in Angiogenesis and Invasion of Human Urinary Bladder Cancer, Cancer Research 64 (2004), 8932-8938.
  • Eroğlu M., Irmak S., Acar A., Denkbaş E.B., Design and evaluation of a mucoadhesive therapeutic agent delivery system for postoperative chemotherapy in superficial bladder cancer, International Journal of Pharmaceutics, 235 (2002) 51–59.